Hi Durinko,
Preflop: 4-bet bluff versus an unknown 3-bettor is fine and the size is good as well (22-24 BB range). However, this villain may seem a bit fishy (39/16) so I wouldn't want to 4-bet bluff versus players like him.
Flop: Once he calls us I normally shut down. Players like to call Ax hands and certain pairs.
I would simply fold here as there isn't much we can do.