I took this from HEM:

I got dealt QQ+ 4561 times over 338923 hands. So, considering that every hand I played was in a full short handed table AND disconsidering things such as table image and metagame. That is, if we take the statistics in a vacuum:

Over 338923 hands I'd have played 56487 orbits. Since I pay 1.5bb per orbit, I'd have paid: 84730bb.

My winrate with QQ+ is 597bb/100. So, over 4561 hands, that's 27462bb.

As you can see, even under ideal conditions, it's hugely -EV.

If you also take into consideration that players will adjust to your strategy, it's impossible to win