PLO25 fatality on the river

Fold preflop, nothing else to say on the hand.

KQ64 is just an awful, awful hand and you should never be seeing a flop with it unless you posted the big blind.

I really don't understand what you're trying to achieve by calling preflop when UTG raises and 2 people call before you. This isn't holdem where you can talk about "getting 5 to 1 on the call". This is PLO where there is a huge amount of reverse implied odds with this call.

You're going to lose a big pot when it comes KK7 and villain has AKxx.
You're going to lose a big pot against better flushes.
You're going to lose a big pot when you hit 2 pair because you have no redraws plus you can easily be dominated by a better 2 pair (like on this flop).

Please stop making these calls out of position with terrible cards, it is costing you a lot of money in the long term.

From the hands you post here you are way too loose out of position and you are way too passive in position. Raise more in position, fold more out of position (but fold this hand from any position especially!)