ace high CB

Hand converted with online PokerStrategy.com hand converter:

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$0.25/$0.5 No-Limit Hold'em (6 handed)
Known players:
[tg]BU$69.49:///////;SB$61.04:///////;BB$87.48:///////;MP2$43.39:///////;MP3 (Hero)$49.50:///////;CO$112.58:///////;[/tg]
Preflop: Hero is MP3 with A:h, Q:d.
MP2 folds, Hero raises to $1.50, CO calls $1.50, BU calls $1.50, 2 folds, BB folds.

Flop: ($5.25) 4:c, 9:c, 3:s (3 players)
Hero checks, CO bets $3.00, BU calls $3.00, Hero folds.

Turn: ($11.25) 9:s (2 players)
CO bets $5.25, BU calls $5.25.

River: ($21.75) 5:d (2 players)
CO bets $12.50, BU calls $12.50.

Final Pot: $46.75.

CO　in ２２　hands vpip23 pfr9 af2 wtsd80 w$Sd25 BU unknown 　　　　

should I CB with ace high? I also want to know against 2 unknown players