I think that this is an area that could potentially give you a bigger edge if employed correctly. Poker for me is as much about psychology as it is about maths, even online. I've been toying with this for a while and I see some good results - at least it definitely hasn't hampered my game.
For example, I had this guy to my left who'd almost always push all-in from BB whenever I limp from SB in an unopened pot (he was shortstacked in an MTT). He must have had a range of 80% or something. I limped from SB again with 95o and wondered if I could talk him into seeing a cheap flop. I simply said "watch out, I could be trapping!"... sure enough the hand was checked down all the way to the river. As it turned out, he definitely had a hand that he could and would have pushed me with (given his range) - KTs. Next round I raised him (I had KQs), he folded, and I said "34o that time lol".
One of my other favourite methods is trying to force the big stack out of his comfort zone and induce mistakes out of him... after all, he's the biggest source of money on the table! If he's too tight I'd go something like "come on, you should be bullying us around a bit!". Or if he folds when he's had something like 5:1 pot odds to knock someone out, I go "come on, you could have called with any 2 cards there!". If he's too aggressive I pick a spot and re-raise him, then I show my bluff and say "next time I can do that with Aces.... or not".
Like I said, it's all about getting people out of their comfort zones, getting them to play in a way they otherwise wouldn't. Subtle, playful one-liners are my weapon of choice. The only obstacle is when I'm not really in the mood.. because I don't want my lines to sound forced or too "mechanic"... I definitely need to be "feeling it".
I know there is a "mute" function and all... but I doubt anyone uses it at all unless someone is extremely annoying or spamming.
Thoughts?