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PL 5 Card Omaha 0.50(BB)
HJ (73BBs) [VPIP: 26.4% | PFR: 13.7% | AGG: 32.1% | Hands: 2503]
CO (263.6BBs) [VPIP: 26.1% | PFR: 16.4% | AGG: 29% | Hands: 2600]
HERO (176.8BBs) [VPIP: 27.5% | PFR: 20.1% | AGG: 25.9% | Hands: 94462]
SB (100.6BBs) [VPIP: 23.7% | PFR: 14.1% | AGG: 19.3% | Hands: 3729]
BB (56BBs) [VPIP: 27.5% | PFR: 14.4% | AGG: 34% | Hands: 2637]
I would usually fold this hand pre, but with only regulars on the table and also having a tight table dynamic I decided to make a play.
Villain is a solid regular, with semi-loose pre stats but tight postflop continuation vs. hero over 1k hands:

Dealt to Hero: 2♦ 5♥ 9♥ A♠ J♠
HJ Folds, CO Raises To 3.5BBs, HERO Calls 3.5BBs, SB Folds, BB Folds
Hero SPR on Flop: [20.38 effective]
Flop (8.5BBs): 6♥ A♦ 7♥
CO Bets 6BBs (Rem. Stack: 254.1BBs), HERO?
Spoiler
HERO Calls 6BBs (Rem. Stack: 167.3BBs)
Turn (20.5BBs): 6♥ A♦ 7♥ 8♥
CO Bets 13BBs (Rem. Stack: 241.1BBs), HERO?
We have the invulnerable nuts.
Spoiler
HERO Raises To 29.7BBs (Rem. Stack: 137.5BBs), CO Calls 16.7BBs (Rem. Stack: 224.4BBs)
River (80BBs): 6♥ A♦ 7♥ 8♥ T♣
CO Checks, HERO?
Spoiler
HERO Bets 60BBs (Rem. Stack: 77.5BBs), CO Calls 60BBs (Rem. Stack: 164.4BBs)
I bet 3/4pot as it is my default sizing on blank flush runouts and I did not design an extra strategy just for straightflush possible runouts (and probably never will lol). Since it is a regular I restrained from using an exploitative sizing like pot or betting small to induce (which probably might have been a better play against the particular hand since he would give action with the Ace-flush (which is second nuts as we remove-block other straight flushes), if he still just calls in a nitty way I basically just lose value though.