$100 QTo fifty50

statistics? reads? Any information at all that would lead us to think calling QTo against a middle position open raise 20bb effective in a risk-averse DON is going to be profitable? Although we are technically in last place, there's plenty of time for others to make mistakes; we don't need to make their lives easier.

in the absence of such information, I would say this is an easy fold preflop. We are completely dominated by his opening range.

As played flop bet is okay, but I don't mind checking behind either since he's giving us a free card and we hate life when he check raises. I think your river bet is too big on this scary card. He is either slow playing or has a pretty marginal holding which he won't call for this size. 1/2pot looks good.

This raise smells like backdoor flush draw or turned full house to me and I don't see any reason why he would be bluffing the River, so I fold and hate myself for calling pre in the first place.

fold PRE . this is a HUGE leak.

river is a bet/fold