When stacks get deep in PLO, holding or drawing to the nuts becomes more important. Therefore, for example, small pairs go down in value (because they generally flop second or third set and can be dominated against top set) and lower flushes go down in value.
It also becomes more important to have redraws when the money goes in when you are deep. For example, on a 6 :heart:7 :heart:8
board, 239Tr (the current nuts) will be crushed against something like 9 :club:T :club:J :heart:Q
which has a redraw.
A hand like J :club:J :heart:T :heart:2
is very weak and should generally be folded pre-flop both shallow and deep. There are however situations when it can be played profitably (e.g. multiway and deep vs fish) as it has good potential to hit top set.