ICM explorer says that if he's on a 25% range (which I think is reasonable given the other big stack might do something stupid) it's a (close) fold.
Oh yeah and the UTG+1 is a good reg on the limit.
Grabbed by Holdem Manager
NL Holdem $400(BB) Replayer
SB ($6,250)
BB ($2,060)
UTG ($1,790)
UTG+1 ($7,450)
CO ($1,480)
Hero ($970)
Dealt to Hero A♦ 4♠
fold, UTG+1 raises to $7,450 (AI), fold, fold, fold, fold
UTG+1 wins $1,000