Looking to learn PLO, what is a good learning pathway?

Drill lot of preflop first. Recommend plotrainer/skills for that as it's also free for preflop.

Then play and post hands actively when feeling unsure. Some of basic postflop principles can probably be found for free.

Yes but how do you drill PLO HU preflop, isn't it very opponent-specific?

Sure but I would not worry about HU ranges specifically. High rake on smaller stakes tend to make it questionable in first place. E.g. you need to play lot of hands ending up paying lot of rake and this combination with new format is pretty bad imo.

But you can start with BU open range in trainer which is around 50% of hands. Then widen from there by looking what sort of hands are quite not in that 50% range. Theory wise HU open range is around 85% I think. Now if opponent is tight you may want to open very close to any4 as well. But that also kinda apply in SBvsBB versus way too tight player. In general open ranges are opponent dependent especially on late positions, e.g. from CO onward.

Good example could be that I personally open all AKxx combos on BU as default. But if blinds are calling or 3betting a lot then I start to drop some of weaker combos.

In general skills is very nice wat to train open ranges but in trainer you can also approach it from hand categories. Or something like to do sometimes is find general simplifications. E.g. check how much JT9x opens from each position. Main point though with preflop is repetition and it's sort of neverending work that tend to pays off. I personally do 50 hands on skills before first session of the day always. Plus tend to "mark" (with qyazo in Unibet) bunch of those preflop spots during sessions.

NL2 HU it shows +7bb/100 or +24bb/100 allin EV for 2,200 hands. But total winrate is about +25bb/100 for 12,000 hands in NL2. I believe PLO2 HU can be easily beatable, but yes, maybe 6-max is more profitable. You get more hands/hour though in HU. Not much worried about rake.

Thanks for the tips!

Remembered that I read jnandez ebook when I started. Title was something like "how to beat small stake plo" or so. It was compact introduction for the game.

Jnandez's book is good starting point, I think it doesn't cost almost anything nowadays. Should be available as e-book. Micros HU PLO is a rake trap, you need to be a lot better than your opponent to beat the rake. And there aren't really HU tables, it's often normal table with just one player. And if he is waiting there, he is likely a decent player and no one wins in the long run. My advice is to stick with 6max, and once familiar with ranges and common strategies, then start to think how HU differs from it.

There is also an option to learn preflop for free, as stated here: https://forums.pokerstrategy.com/forum/thread.php?threadid=431398
It still works, so if you are looking for free stuff I recommend that. If you hafe few bucks to spend, those solver preflop apps are better as you can easily visualize more than just one hand.

Yeah havent found a good PLO2 cash table, on most sites it starts from PLO4, on Party there are regs tablestarting PLO2 as you said, so I quit that site as protest. Will be back soon if roll bigger, deffo wouldnt want to lose $10 or something playing plo cash.

I found that Upswing's PLO launchpad was a great introduction to PLO coming from NLHE. I think I'm now very comfortable at 25PLO.